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Combining acid/base chemistry, cell biology, and quantitative research methods, this “egg-ceptional” activity promotes a truly interdisciplinary perspective. First, students find out what effect acids and bases have on calcium-based substances such as eggshell and bone. Second, they discover what changes occur when decalcified eggs are placed in solutions of water and corn syrup. Throughout the two exercises, student groups will be measuring, analyzing, and using data to reach valid conclusions.