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The example of Models-Based Science Teaching (MBST) the author presents in this chapter is built upon the guided inquiry model. Inquiry has shown itself to be at least as effective as traditional approaches for content acquisition and better in creating positive student attitudes toward science. On its face, inquiry also better mirrors the practice of science than traditional approaches. Our purpose is to impose a framework that develops other elements of science literacy as well, specifically understanding of the nature of science and its personal and social contexts. Building upon inquiry makes good sense, but you could infuse elements of MBST into a more traditional curriculum. This sample chapter also includes Table of Contents, Preface, and Index.